Extraction of Bioactive Compounds from Coleus amboinicus for Non-Steroid Inhaler Development

ABSTRACT:
Coleus amboinicus, commonly known as Indian borage or Mexican mint, is a widely recognized medicinal plant celebrated for its diverse therapeutic properties. It exhibits potent anti- inflammatory, antibacterial, and antioxidant activities, making it a valuable resource for various medical applications. The plant is particularly rich in bioactive compounds, including rosmarinic acid, thymol, carvacrol, and flavonoids, which hold significant potential for enhancing respiratory health. These natural constituents have been extensively studied for their ability to support the respiratory system, reduce inflammation, and combat microbial infections, thus offering a holistic approach to respiratory care. This review focuses on the development of efficient and cost-effective distillation methods for extracting these compounds. By employing simple distillation techniques, it is possible to isolate and preserve the bioactive components in their most effective form, ensuring their therapeutic potential is retained. Furthermore, the review explores the integration of these natural extracts into non-steroidal inhalers, presenting a safer alternative to conventional steroid-based asthma treatments and therapies for other respiratory disorders. Such non-steroidal inhalers represent a groundbreaking fusion of traditional medicinal wisdom and modern technological innovation. They aim to provide holistic respiratory care by leveraging the plant’s natural healing properties while minimizing the risks associated with long- term steroid use. This approach underscores a commitment to advancing medicine by bridging the gap between age-old herbal remedies and contemporary medical advancement.